I cannot believe I have never heard of this before, but after seeing this story at Ain’t It Cool News, I am very, very stoked.
Based on the novel by Philip K. Dick, the IMDB sums up the plot as:
Set in a future world where America has lost the war on drugs, undercover cop Fred (Keanu Reeves) is one of many agents hooked on the popular drug Substance D, which causes its users to develop split personalities. Fred, for instance, is also Bob, a notorious drug dealer. Along with his superior officers, Fred sets up an elaborate scheme to catch Bob and tear down his operation.
Sounds great to me, but the real kick is what it looks like: WOW! They have taken live film, and graphic novel artists are animating over it and it just looks great, check out the pics at the bottom of the page!
Neat!