A lot of place, especially in Europe, had to cope with rebuilding after WW2. In the anime, taking place in Japan, obviously it’s reminiscent of their rebuilding; however, that is still a universal theme of the aftermath of war that people across the world have endured.

“the 1980s student riots (they just switched Narita airport with the Olympic stadium for the comic/film)”

Again, same thing. Taking place in Japan, this is a relation that we can connect it to; however, it is still a universal theme. Rioting is experienced across the world, and its tragedies and impacts are felt by people globally. Another universal global theme here. Thanks for pointing that one out.

“the unwanted intervention by American forces (in the manga, I think was cut from the anime though)”

Can’t really comment on this, as I’ve only seen the Anime… which was the first anime I ever saw way back in the day. Even then, any time any country’s unwanted intervenes in another countries business occurs these theme shines through. Not just with American interventions, but such groups as the United Nations is also looked down upon for many of their actions. Another universal theme; whereas the Anime taking place in Japan the most obvious to look at is the one you stated.

“the uncontrolled spread of capitalism within the power vacuum”

Another universal theme and not just applied to capitalism, but any government establishment. I remember a time when a little thing known as Communism was spreading and being saw it as a threat.

“the financial crisis”

Hey, look around… even now this is a universal theme. The world is kind of a financial crisis as we speak. Japan is not the only effected by this.

“there’s no mistaking the connection between the opening explosion and Hiroshima.”

This is true. But do you know what those bombs meant? They meant power and mans ability to destroy in a globally threatening like never before. Japan has felt the force of that sadly, but this is a global threat and could occur anywhere. This was not just a tragedy for Japan, but a tragedy for mankind. This is once again a universal theme.

Thanks for strengthening my argument. Provided me a path to show the universal nature of the Akira story. Let’s not forget the universal themes shared with Blade Runner in the acknowledgment of man’s desire to bring technology to new heights. If we see the way to achieve something, that we will do it despite the cost it may have on our own morality.

If they want to make an Akira like story set in America fine, but don’t call it Akira.
I think there is a difference between super heroes being cast as a different race and Japanese or any other Asian or non-American story cast with American actors. I feel the same way about Death Note being adapted for America which will likely star American actors.